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KMID : 0366220050400030197
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Korean Journal of Hematology
2005 Volume.40 No. 3 p.197 ~ p.200
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A Pediatric Case with CMV Gastroenteritis after Donor Leukocyte Infusion
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Song Ae-Kyung
Kim Hee-Jun
Jung Hyun-Joo
Park Jun-Eun
Jeong In-Ho
Park Joon-Seong
Kim Hugh-Chul
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Abstract
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There haves been few reports of cytomegalovirus (CMV) gastroenteritis following allogeneic stem cell transplantation, especially in pediatric cases. Herein, we report a case of CMV gastroenteritis in a 10-year-old boy with relapsed juvenile myelomonocytic leukemia who had undergone a donor leukocyte infusion. He presented with a skin rash, diarrhea and abdominal pain following a donor leukocyte infusion. Cramping abdominal pain persisted, even after treatment of the acute graft-versus-host disease. Therefore, gastroduodenoscopy and a gastric mucosal biopsy were performed, after which CMV gastroenteritis was diagnosed. The boy recovered after treatment with ganciclovir and intravenous immunoglobulin.
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KEYWORD
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CMV Gastroenteritis, GVHD, Donor Leukocyte Infusion
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